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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3364db1df87ceca8cc03a65d6c305a9761e643bc09c9ea48765cf398401a80e' 
  AND token = 'f6+aJXNYnjPR0NYNCBAYkvO95uYP9sVmemQyN3qMROw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}