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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af822d5f52ee9857328c3b6550f66866600046f35767fa712473971ca8d9ad47' 
  AND token = 'iLxuzNqUbF3L/r8irKneAjwu33Uu0LnR0VvZwaoDtHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}