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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27ab5d5a1032a1b19e665b975410f98f2963604e523a6990b87db5e8ba04a19d' 
  AND token = '90Y2PMkk/JDOAQ5kh0AKgdZ2W9j7jYjS+x4TOf1coUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}