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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2143087b5906c63388287840b19ede623f9017b9e224fc97600249e1f44cfbc7' 
  AND token = '/5eOhDEpm/TIuUFDeYe9iB90JYXah9T9Bf3Lfdv9bUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}