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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f649dcb5cb9bad98d7690a383006449e5ec99eeb3a833ce5cdd221983f536089' 
  AND token = 'lQlcsC6GWDmnpG90gAO91Om3uUT/xwwW3t8svXisQz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}