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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9440f43a531251dfc582efb3c19e7df4c0b11d2be4084a754498dbb6b6a305a7' 
  AND token = 'PNay+jg6xGJ3JNg8MugWUA+5/1e2djCvS7PHsXVaEl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}