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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d599db58709d52c5ee50e89490a6cf35cbff50e4f7fc770d5f1212630b7640' 
  AND token = 'CIdD1zuQTZNDaqimb5p7lBRjvlqCLtrSc6TIq9RYnWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}