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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2729c2216c146ba9f64345f3a662b47c4745f8e2dfc83dc334c903c8e267449d' 
  AND token = 'mdaf6ZcVrA6avOwDbK3oWbQi7q+62aZP4W//UWkWyaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}