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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dfabf2a476bdcd06017f20df20c3864a21d39bb0933e16dcc03aaf5213dd795' 
  AND token = 'JrmbcbMtaFhA/8PNNyVT7uaH2TbchbBFF3Sj0irsewI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}