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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a9dcf15b54b80ba0499f00e0bf4d96a49b325d2b2345dccbabd681a05bf73f3' 
  AND token = 'Vz2OUJyaSXv5yAKT9RRbB1fllSj1yL/AdxGLj6HFDXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}