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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95e9096ded1c23aadb59e9e3ef1ef28fed3b67e791e4a1f9ba4aeaa52293dc33' 
  AND token = '3Vt/xtipfuB3iI+lbARJmya4Lj8VcEMSce3LDTCxCoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}