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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c580862c184933382f6ce4d09a950f49e73794e9e1c88f3d39138de6b6c805a2' 
  AND token = '7LIAxPfXZsbKyHswWyEsZJ9lounG/U/2ve0LXchtdvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}