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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a88002bd0540b581458e5b36bb94d1c87ce16af9be345de77c3ccab0eabce30d' 
  AND token = 'bBZ2gjkdWnoPrBEOw04cnsuTublf8jzTGMv+709WzO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}