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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13764676bf1adeb5a816ec48c6d4c18266468c7d3e5fc0a57570a66851f148b1' 
  AND token = '5y/osB0u87ZGTgLTIxIMJJDWS75086bdsaF9vuDmw40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}