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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e278c3ed8bfab2c1de52231fa6462c945e7032e43bcdde2de1a0230f2b8de666' 
  AND token = 'lQuoklw9K+D55pKGwb6YpqeESFtciSbzHley1yvtChU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}