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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '192ff22a5bce76238c9ab4787d6e03830d77e2f7f5407544e8762e5b222ee12f' 
  AND token = 'tEypjUukxnVS2Wh2nU6RYyxG0xvTsFhl0gs3F8Eidqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}