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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b33731d0f3c7d058664ae50014d36d185d92a19b5da14544c12d554c2c3b7a9c' 
  AND token = 'YE1XVIve28zlGr8FdfuKzNWnOT8A2S3lYn0gKz4Ran8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}