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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cd0d99208003efd2663c2cd9c463a29f50f4c6b8234bf26173be0d1e43eccc2' 
  AND token = 'D25FBzQZhHGG2yVZy3KhRCyfHpmtm+GNAa5P8Pxu1/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}