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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b99baddcf84130d9d607381d625174fa847a98bc9f91f05d93bc77a4451af9' 
  AND token = '2vpoJKUZd+YpR1D82tk/cdlgRvvgaJgDPUP1MLtY/E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}