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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49df728ac833460dea019d2863fe590fc498e8c90a411319c8dac20100c7ecf4' 
  AND token = 'eE/mdVRVUl0X8FdlU3bAiMLXNGSd9Z9MTLLT3gz3dfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}