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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3901915559ed2531a7bb6676f30a804ac7fa2729dd26de4c35f4b456797c9a45' 
  AND token = 'cv7RtpyFqX8s6zDTnLy90T6mQjQGePuajHgNOJLt2Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}