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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6501cb9207e8368111c0ef642e923a29c542dd52511a42bf818bd613650bf81' 
  AND token = 'BoXmPUkWVfTbeRj5eMjX5aW/CsUxaIzqRAcw+Km0Y6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}