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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e958d5e4049cad5ce8b249ef148e228d29e7941846b0e37e2d39934ebe112a5d' 
  AND token = 'H2h6Gs4c4wQcIVJHk0jDF+TDmZCOWR1Z+bfbBwhggL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}