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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'feaa74a2da24c3d2ed36a24930eb5ff21fb0e922dcf5297dfde95e43568fc44c' 
  AND token = 'ifY5F51vOd3EQg2/p4zDDCLu9hbNVVQnv1Nrqrfs27I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}