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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be72d3252654038d3ed25b20036df89ec0278d014902417eea9e1d0564a4b6f5' 
  AND token = 'MRS3kbtzSKKU2KmupTTtJbzXWue2LfwkAdCl0IJg9mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}