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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bb16609d1c879dcb8dab3fdaf88635b56f55d3909df44fb3fd7f4552eaf17a8' 
  AND token = 'dKWlzMbTT0L+raeTGfw3JIQRPV0lVpfT/mEpYZzBexQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}