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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b088299a4df801d6c6d046064e151dbc2de57aa9c2e729d8db4d42f27e15a5d3' 
  AND token = 'sljs8aRL31gjFcaYH2uIJ7GO7+IDpcb4vUxkj/Q2z5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}