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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3249412427a36a22beafa4da9bcc155762d9fa49d3fcea2ce1e5d82a204599' 
  AND token = 'KvLsF07xjfpUQY+YLQ7oD3iKD8J4VkhHfAJvuG2EmFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}