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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43254959a4c89d495cd8568a4fbc0366d6a6c8b34faf946aaafb83d5572d815f' 
  AND token = 'n4CHInHZBNIsZafMg0BUkwPHhNsmiVVxwXRyMoOjqow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}