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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a9858a48c07d89235da5d0a64845f81bf1e9fc970569dbec5ca5f28c9cf1b5' 
  AND token = 'ZQVXoQYGO3pN82tnko6cTDwzd/71OPN+ow5SpO8YxgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}