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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1870dc4d872b405da46dce126ff94f2201c67cbdf46cc2439a3eb24b065649c' 
  AND token = 'l8Y1pdhhB2PEU3VcYXXHw0SVFMl8UBYJKU3n4BC0nho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}