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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd541f4550d180cff684d80ceee09d381e355ed8507512fb82030927a6990f2c6' 
  AND token = '/GHJVP+nCSA7fQR30ES2/SxcNL/29IWX7aQ0hEBxQ1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}