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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44eebb9fe6a80c625b0dd5e8b0f5cb35647d57acb97dbe76b5840fd97e171f01' 
  AND token = 't6QEKBsX3WNkt7RPChUC9JY0IHcLvztFu2mpfWo3JqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}