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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd65bf7a76dfe7d9f7113bf130affa6a22a3b9f6bc5c6007ec3be0257ad3fce49' 
  AND token = 'KsM+i+UCjOil8coTW4H79y+daWDMeyBEOTPJOqIgV+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}