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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20637bc9fcdb3839125a4488fff182e092bf5a2499999469c8634c85306664b1' 
  AND token = 'q684sY3UNDmAygxDrWmO/kttpb0X3XeZp3DHxCbLgws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}