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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0857e0f4c2fdb14d2745d17db780e80d88b2dddb139b85f206b21bba35b6c622' 
  AND token = 'DGWNAHGlAImRpxQanx81zpOhWGzqHfb+xw16Hi0jk2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}