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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b2c6622285e8d8d18f725f04bac6b23125f27bb778f2b1f3b0db255c86e8a71' 
  AND token = 'X9ZgPXiSiW8T3tg3hDGbWA9Scr1FqbhRWwbJgVzD0Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}