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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c33bbb111d41ec317bbdadc203dff3e303e7446e8ba7a4b674dd59d82832ffa' 
  AND token = '0ATuIW75l01DhVVdV6zRtRHR/LUYy4OioU2WzJ04AvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}