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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d80a3a36d8e2a8f832c9e8e8d06e3b01ee606b15eb0f37a73ea47ee35b4b89' 
  AND token = 'lX01s4GMOKBZ+GO+8ap9TkoNz7hRjw5E7JYxGruoHZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}