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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac69e57cb311cad21978baf88a6a4f08296fb8197c8e2d4d025f94936b49ac8f' 
  AND token = 'HQ4dtpc1hB8e7gl7CE7XzaiHxsWdzaOtD0nwNwowe2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}