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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21761eb650f16f5666dc8cfefe07861924c0b931ff18a62a15bb0e50f57ca3b' 
  AND token = 'gLwwZvsSm3wWSeBS6lF5Ad6YhWIbUxEIr2PXAVRC69E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}