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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0d4a15015b171b1c1e4b124c64a34e6a04295f8b2b06804bb53c9b254b6a16' 
  AND token = 'nBru8lTfy1sCQUqhY8mgXMHpod2F/w45nJDDalHlr2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}