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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f6a7ae33a753e49aa838a3c5f29a6d5cff56712b81f9e2413838fbc43605c37' 
  AND token = 'JSa44jLTEXtujABW7YCGrOQdWq04qjgTAYLL3O9OhDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}