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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd07b5152d91b07afd66fd15aa1d4a6cdec22aeb8adc4a35344db45572ca4ae08' 
  AND token = '0HvP511hS3eEismflHztL11KxM4UwrSOFe4InvUGn3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}