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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '873f47c37a106dab2b4421a5b2852869f980791da1e62a023057032197541f6c' 
  AND token = '1s2i4aUuFtKnSRY4MXSMbzYT08QuP4UDGypDpxAHKNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}