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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e51c638f28b6fac3b1a512b150a3a4398ca98813a4f6f82d9818765f77aaa60' 
  AND token = 'so9vMHwtxMYcpu/rRz82ka3lLi6KlyW+qrpgcvqzHts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}