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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26c03633c031aea45d3113cfe41a205b69b30560024678b6d34e0e9e0798eaf2' 
  AND token = 'ZasdPFTKhDpc2uUTXYHvsyrQbtvCSFfA6Abps3mPpyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}