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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e7cda25c51e3f5b63f351a9123216f7938b4b0b3c5be1447215dc1ecabfc07' 
  AND token = 'duihzLVlIFsvNy6TOwftBJCeXnZ2422bINMBUgn2XRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}