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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8186e0637e4c0afb2356462f646c28844bd74a04e78d5413a3a08e17571509a8' 
  AND token = 'N2mMxJmyqIN2b6CRAhztKBK10iKkyr79cq7VpLYqnbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}