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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63bd0620d695464e91dd224a9436e9e7806f30cc331a70e53c6f08cffe366867' 
  AND token = 'izWR0YyJRoF+GlbkTueh6fGfAiOzazE5l5juDuJL6WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}